• Biography
  • Research
  • Lab Members
  • Funded Projects



Professor, Director of Mr. & Mrs. Ko Chi Ming Centre for Parkinson’s Disease Research.

Program Director of BCM & BSc. BIOMED, Teaching & Research Division, Associate Director of Clinical Division.

Expert in Chinese Medicine, Pharmacology of Chinese Medicine, Neurodegenerative Diseases.

limin@hkbu.edu.hk



Limin.pngProf. LI Min obtained her Bachelor's degree from the Henan University of Traditional Chinese Medicine (TCM), China, in 1985, her Master's degree in Chinese Medicine at the Guangzhou University of Chinese Medicine, China, in 1988 and her PhD degree in Cardiology at the School of Medicine, Tokai University, Japan, in 2001. Then she joined the School of Chinese Medicine, Hong Kong Baptist University, where she is currently a professor and serves as the Programme Director of BCM, an Associate Director of the Clinical Division and the Director of Mr. and Mrs. Ko Chi Ming Centre for Parkinson's Disease Research. Prof. LI received an Award of the Distinguished Female Chinese Medicine Practitioner by the China Association of Chinese medicine in 2007, School’s Award for Outstanding Performance in Scholarly Work in 2012 and President’s Award for Outstanding Performance in Teaching from Hong Kong Baptist University in 2013. Prof. LI’s clinical specialty is in Chinese medicine treatment of neurodegenerative diseases, including Parkinson's disease (PD), Alzheimer's disease (AD) and vascular dementia (VD), as well as on cardio-cerebrovascular diseases.







Prof. LI’s long-term research interests are:

● Neurodegenerative Diseases Including Parkinson’s disease (PD) and Alzheimer’s Disease (AD).

● Chinese Herbal Medicine for Prevention and Treatment of Neurodegenerative Diseases.

● Development of Molecular Targets for Drug Discovery from TCM for Neurodegenerative Diseases.



Prof. LI’s current research directions are:

● Investigation of the Efficacy and Safety of TCM in the Treatment of Neurodegenerative Diseases including PD and AD based on Randomized Controlled Clinical Trials, as well as the Interaction of TCM and Western Medicine.

● Understanding the Neuroprotective Effects and Underlying Mechanisms of TCM on Neurodegenerative Diseases including PD and AD.



Principal Investigator

 


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  Prof. Min Li (M.D. & Ph.D.)


  Director of Mr. and Mrs. Ko Chi Ming Centre for Parkinson's Disease Research
  Program Director of BCM & BSc. BIOMED, Teaching & Research Division

  Associate Director of Clinical Division

  Chinese Medicine, Neurodegenerative Diseases, Cardiovascular Diseases,

  Pharmacology, and Randomized Controlled Clinical Trials

  E-mail: limin@hkbu.edu.hk









Research Assistant Professors


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  Dr. Siva Sundara Kumar DURAIRAJAN (Ph.D.)

 

  Research Assistant Professor

  Neurodegenerative diseases, Molecular Pharmacology,

  Autophagy & Lysosome Regulation, Neuroprotection, and Chinese Medicine

  Email: dsskumar@hkbu.edu.hk

           


           


                        

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  Dr. Ju-Xian Song (Ph.D.)

 

  Research Assistant Professor  

  Neurodegenerative Diseases, Autophagy & Lysosome Regulation, Neuroprotection,

  Molecular Pharmacology, and Chinese Medicine

  E-mail: s189721@hkbu.edu.hk


 






Ph.D. Students



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  Mr. Liang-Feng Liu


  Ph.D. Student

  Autophagy Regulation, Neurodegenerative Diseases, Neuroprotection, and Chinese Medicine

  E-mail: liongphone@gmail.com


 





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  Ms. Lei-Lei Chen


  Ph.D. Student

  Neurodegenerative Diseases, Autophagy Regulation, Neuroprotection, and Molecular Pharmacology

  E-mail: leilei.chen2011@gmail.com







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  Mr. Ka Kit Chua, Tony


  Ph.D. Student

  Neurodegenerative Diseases, Randomized Controlled Clinical Trials, and Chinese Medicine

  E-mail: kyo1212hk@hotmail.com







Research Staff



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  Dr. Tao-Hua Lan (Ph.D.)


  Hong Kong Scholars

  Cardiovascular Diseases, Atherosclerosis, Autophagy Regulation, and Chinese Medicine

  E-mail: luckyblue1982@126.com

 






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  Dr. Chuan-Bin Yang (Ph.D.)


  Senior Research Assistant

  Autophagy Regulation, Neuroprotection, Molecular Pharmacology, and Chinese Medicine

  E-mail: yangchb@hkbu.edu.hk


 





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  Dr. Ashock Iyaswamy (Ph.D.)


  Senior Research Assistant

  Neurodegenerative diseases, Molecular Pharmacology, and Chinese Medicine

  E-mail: ashokenviro@gmail.com








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  Ms. Ying-Yu Huang


  Research Assistant

  Neurodegenerative diseases, Neuroprotection, and Chinese Medicine Quality Control

  E-mail: wongwingyu@hotmail.com








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  Mr. Sandeep Malampati


  Senior Research Assistant

  Neurodegenerative diseases, Neuroprotection, and Pharmacology

  E-mail: deepu.pharma08@gmail.com









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  Mr. Sravan Godalakrishna


  Research Assistant

  Neurodegenerative diseases, Neuroprotection, and Molecular Pharmacology

  E-mail: sravangs@gmail.com



 








Previous Lab Members


Prof. Fu-Long Liao

Prof. Dong Han

Dr. Chi-Ho Chung

Dr. Ming-Qi Zhao

Dr. Chi Zhao

Dr. Li-Xia Xie

Dr. Wan-Fung Kum

Dr. Jia-Hong Lu

Dr. Xing Yu

Mr. Wai-Leuk Fong

Ms. Yan Wang

Mr. Sui-Cheung Man

Mr. Yuan-Chi Lam

Ms. Yu Zeng












 

 

Funded Projects


Project 1

Title: Understanding the molecularmechanisms of Corynoxine B in promoting autophagy and neuroprotection: Targeting HMGB1-Beclin 1 interaction

Principal Investigator: Prof. Min Li

Funding Body: Hong Kong General Research Fund

Project ID: RGC/HKBU-121009/14

Exercise Year: 2015/2016

Approved Project Duration:24 months

Project Fund:HK$ 564,833

 

    

Project 2

Title: Combined Use of ChineseMedicine Decoction (Tianma Gouteng Yin) and Sinemet for the Treatment of Parkinson’s disease: Preclinical Evaluations on Safety and Efficacy

Principal Investigator: Prof. Min Li

Funding Body: Hong Kong Health and Medical Research Fund

Project ID: HMRF/12132091

Exercise Year: 2015/2016

Approved Project Duration:24 months

Project Fund:HK$ 999,600


    

Project 3

Title: Chemical modification of oxindole alkaloids from the Chinese herbal medicine Gouteng for the optimization of anti-Parkinson's disease activity

Principal Investigator: Prof. Min Li

Funding Body: Hong Kong Innovation and Technology Fund

Project ID: ITS/274/12

Exercise Year: 2013/2015

Approved Project Duration: 18 months

Project Fund:HK$ 999,925

    

Project 4

Title: Functional Analysis of Isorhynchophylline in Promoting Autophagy and Protecting Neurons

Principal Investigator: Prof. Min Li

Funding Body: NSFC / RGC Joint Research Scheme

Project ID: N_HKBU213/11

Exercise Year: 2012/2015

Approved Project Duration: 36 months

Project Fund:HK$ 794,840

    

Project 5

Title: Chinese medicine for inflammatory bowel disease and Parkinson's disease: study about the efficacy and its underlying mechanism

Principal Investigator: Prof. Min Li

Funding Body: Interdisciplinary Research Matching Scheme of HKBU

Project ID: HKBUIRMS/12-13/1A

Exercise Year: 2012/2015

Approved Project Duration: 36 months

Project Fund:HK$ 687,500

 

Project 6

Title: Natural Neuronal Autophagy Enhancer Schisandrin B: Molecular Targets and Neuroprotective Effects

Principal Investigator: Prof. Min Li

Funding Body: Faculty Research Grant of HKBU

Project ID: HKBU/FRG II/13-14/094

Exercise Year: 2014/2015

Approved Project Duration: 12 months

Project Fund:HK$ 120,000

  

Project 7

Title: Restoration of alpha-synuclein-mediated autophagy deficiency in Parkinson’s disease by natural autophagy inducers

Principal Investigator: Prof. Min Li

Funding Body: Faculty Research Grant of HKBU

Project ID: HKBU/FRG II/12-13/038

Exercise Year: 2013/2014

Approved Project Duration: 12 months

Project Fund:HK$ 135,000

  

Project 8

Title: Development of a mTOR-independent activator of TFEB for the treatment of neurodegenerative diseases

Principal Investigator:Prof. Min Li

Funding Body: Matching Proof-of-Concept Fund of HKBU

Project ID: MPCF-008-2014/2015

Exercise Year: 2014/2015

Approved Project Duration: 12 months

Project Fund:HK$ 200,000

  

Project 9

Title: Preclinical efficacy and safety evaluation of Corynoxine B for the treatment of Parkinson’s disease

Principal Investigator: Prof. Min Li

Funding Body: Matching Proof-of-Concept Fund of HKBU

Project ID: MPCF-004-2012/2013

Exercise Year: 2013/2015

Approved Project Duration: 24 months

Project Fund:HK$ 200,000

  

Project 10

Title: Development of a new drug from Chinese herbal medicine on treatment of Parkinson’s disease

Principal Investigator: Prof. Min Li

Funding Body: HKBU

Project ID: SCM/10-11/03

Exercise Year: 2011/2014

Approved Project Duration: 36 months

Project Fund:HK$ 300,000

  

Project 11

Title: Understanding the role of PI3K/AKT/GSK/β-catenin signaling in the neuroprotective effects of Berberine (BBR) on Aβ-induced tau phosphorylation and toxicity

Principal Investigator: Prof. Min Li

Funding Body: Faculty Research Grant of HKBU

Project ID: HKBU/FRG II/11-12/094

Exercise Year: 2012/2013

Approved Project Duration: 12 months

Project Fund:HK$ 120,000

  

Project 12

Title: Phosphoproteomic study of corynoxine, an alkaloid isolated from Chinese medicine Gouteng, on neuronal cell culture

Principal Investigator: Prof. Min Li

Funding Body: Faculty Research Grant of HKBU

Project ID: HKBU/FRGI/11-12/035

Exercise Year: 2012/2013

Approved Project Duration: 12 months

Project Fund:HK$ 40,000

  

Project 13

Title: 柯诺辛对帕金森病的神经保护作用及诱导神经细胞自噬的磷酸化蛋白调控网络研究

Principal Investigator: Prof. Min Li

Funding Body: 深圳市科創委

Project ID: 深圳市未来产业发展专项资金(生命健康类)2014年第四批扶持计划03号

Exercise Year: 2015/2017

Approved Project Duration

Project Fund: RMB50,000

  

Project 14

Title: An In Vivo Investigation of The Therapeutic Effects of Modified Huang-Lian-Jie-Du-Tang and Its Combination With a Western Drug

Principal Investigator: Dr. Durairajan Siva Sundara Kumar

Funding Body: Hong Kong Health and Medical Research Fund

Project ID: HMRF/11122511

Exercise Year: 2014/2016

Approved Project Duration: 24 months

Project Fund:HK$ 904,000

Coordinator: Prof. Li Min

  

Project 15

TitleStructural modification of protopine alkaloid from the Chinese herbal medicine Yanhusuo for the optimization of anti-Alzheimer's disease activity

Principal Investigator: Dr. Durairajan Siva Sundara Kumar

Funding Body: Hong Kong Innovation and Technology Fund

Project ID: ITFS/12132061

Exercise Year: 2014/2015

Approved Project Duration: 18 months

Project Fund:HK$ 1,397,250

Coordinator: Prof. Li Min

  

Project 16

TitleNeuropharmacological and Chemical-genetic Approaches to Investigate the Therapeutic Effects of Yuanhu Zhitong Prescription in Treating Alzheimer’s Disease

Principal Investigator: Dr. Durairajan Siva Sundara Kumar

Funding Body: Hong Kong Innovation and Technology Fund

Project ID: HMRF/12132061

Exercise Year: 2015/2016

Approved Project Duration: 24 months

Project Fund:HK$ 884,000

Coordinator: Prof. Li Min

  

Project 17

TitleDevelopment of NeuroDefend: A traditional Chinese medicine formula optimized for treating Alzheimer’s disease and other tauopathies.

Principal Investigator: Dr. Durairajan Siva Sundara Kumar

Funding Body: Hong Kong Innovation and Technology Fund

Project ID: ITS/253/14

Exercise Year: 2015/2016

Approved Project Duration: 24 months

Project Fund:HK$ 1,400,000

Coordinator: Prof. Li Min





 

 

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